Scaling precision DNA synthesis to empower drug discovery and synthetic biology with chip technology

Navigating the intricate landscapes of drug discovery and synthetic biology resembles the daunting task of finding a needle in a haystack.

To accelerate evolution in drug discovery and synthetic biology, we must cultivate the capacity to generate and assess an unprecedented number of variants swiftly. The basic building blocks for these applications, typically genes and other nucleic acid-based molecules, must be synthesized with high precision and introduced into cells to investigate their function – all of this in parallel for a large number of variants. The cell response must be monitored, and the data processed to select the most promising candidates which are further optimized until the desired effect is achieved. This iterative process necessitates relentless experimentation and analysis. Semiconductor technology, with its prowess in scalability, emerges as the catalyst for this paradigm shift. By leveraging chip technology, researchers can transcend traditional limitations, accelerating the pace of discovery and innovation.